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Interventions for Alopecia Areata

Delamere Finola M, Sladden Michael J, Dobbins Helen M, Leonardi Bee Jo
Cochrane Database of Systematic Reviews. In: The Cochrane Library, Issue 7, Art. No. CD004413
Número: 2913 / Publicado em 10/01/2016 - 13:24

Alopecia areata is a disorder in which there is loss of hair causing patches of baldness but with no scarring of the affected area. It can affect the entire scalp (alopecia totalis) or cause loss of all body hair (alopecia universalis). It is a relatively common condition affecting 0.15% of the population. Although in many cases it can be a selflimiting condition, nevertheless hair loss can often have a severe social and emotional impact.

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British Association of Dermatologists’ guidelines for the management of alopecia areata 2012

A.G. Messenger, J. McKillop, P. Farrant, A.J. McDonagh and M. Sladden
British Association of Dermatologists 2012 166, pp916–926
Número: 2912 / Publicado em 18/10/2015 - 21:54

This document has been prepared on behalf of the BAD and is based on the best data available when the document was prepared. It is recognized that under certain conditions it may be necessary to deviate from the guidelines, and that the results of future studies may require some of the recommendations herein to be changed. Failure to adhere to these guidelines should not necessarily be considered negligent, nor should adherence to these recommendations constitute a defence against a claim of negligence.

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Alopecia Areata Update - Part II. Treatment

Abdullah Alkhalifah, Adel Alsantali, Eddy Wang, Kevin J. McElwee, Jerry Shapiro
J Am Acad Dermatol 2010;62:191-202.
Número: 1992 / Publicado em 20/03/2012 - 08:37

Various therapeutic agents have been described for the treatment of alopecia areata (AA), but none are curative or preventive. The aim of AA treatment is to suppress the activity of the disease. The high rate of spontaneous remission and the paucity of randomized, double-blind, placebo-controlled studies make the evidence-based assessment of these therapies difficult. The second part of this two-part series on AA discusses treatment options in detail and suggests treatment plans according to specific disease presentation. It also reviews recently reported experimental treatment options and potential directions for future disease management.

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Alopecia Areata Update - Part I. Clinical Picture, Histopathology, and Pathogenesis

Abdullah Alkhalifah, Adel Alsantali, Eddy Wang, Kevin J. McElwee, Jerry Shapiro
J Am Acad Dermatol 2010;62:191-202.
Número: 1991 / Publicado em 20/03/2012 - 08:37

Alopecia areata (AA) is an autoimmune disease that presents as nonscarring hair loss, although the exact pathogenesis of the disease remains to be clarified. Disease prevalence rates from 0.1% to 0.2% have been estimated for the United States. AA can affect any hair-bearing area. It often presents as well demarcated patches of nonscarring alopecia on skin of overtly normal appearance.

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